OBN is a not-for-profit Membership organisation supporting and bringing together the UK’s innovative life sciences companies, corporate partners and investors. Their 400-plus Member companies are located across the Golden Triangle and beyond to Nottingham, Manchester and Scotland benefiting from our networking, partnering, purchasing, advising and advocacy activities.http://www.obn.org.uk/
Merck is a leading science and technology company in healthcare, life science and performance materials. Around 50,000 employees work to further develop technologies that improve and enhance life – from biopharmaceutical therapies to treat cancer or multiple sclerosis, cutting-edge systems for scientific research and production, to liquid crystals for smartphones and LCD televisions.
Founded in 1668, Merck is the world’s oldest pharmaceutical and chemical company. The founding family remains the majority owner of the publicly listed corporate group. Merck, Darmstadt, Germany holds the global rights to the Merck name and brand. The only exceptions are the United States and Canada, where the company operates as EMD Serono, EMD Millipore and EMD Performance Materials.
NanoString Technologies (NASDAQ: NSTG) is a publicly held provider of life science tools for translational research and molecular diagnostics. The company’s technology enables a wide variety of basic research, translational medicine and in vitro diagnostics applications.
NanoString’s products are based on a novel digital molecular barcoding technology invented at the Institute for Systems Biology (ISB) in Seattle under direction of Dr. Leroy Hood. The company was founded in 2003 with an exclusive license to develop and market the technology. In 2008, NanoString launched its first commercial instrument system and began international sales operations with its first multiplexed assays for gene expression analysis. In 2010, the company launched new applications for the system to support microRNA analysis and copy number variation detection, and in 2013 launched Prosigna®, its first in vitro diagnostic product for prognosis of early stage breast cancer.
Organizations performing cancer research, biomarker validation and screening, and next-generation sequencing validation are rapidly adopting the nCounter® Analysis System. By providing simple, multiplexed digital profiling of single molecules, the NanoString platform represents a natural, digital downstream companion to next-generation sequencing and enables researchers to embark on studies that were previously inconceivable.
Leading researchers and institutions are finding that NanoString’s nCounter system provides the ideal platform on which to validate their discoveries and translate them into clinically useful diagnostic assays. The nCounter system is uniquely positioned to support translational research because it provides more reproducible results than methods requiring amplification, and generates high-quality data from the difficult sample types common in clinical research, including Formalin-Fixed Paraffin-Embedded (FFPE) tissues.
In addition to continuing to extend the applications for the nCounter system in the discovery, target validation and routine testing segments of the genomics research market, the company’s goal is to become the platform of choice for diagnostic testing based on multiplexed gene signatures that can be offered in hospitals and pathology laboratories worldwide, following appropriate regulatory approvals. These two synergistic areas of business focus provide researchers with a seamless transition from discovery to diagnostics.http://www.nanostring.com/
Founded in the mid-1970s as a collective of scientists committed to developing innovative products for the life sciences industry, New England Biolabs is now a recognized world leader in the discovery, development and commercialization of recombinant and native enzymes for genomic research.
New England Biolabs – putting science first
Created “by scientists for scientists”, NEB is renowned for consistently providing exceptional product quality and unsurpassed technical support. For nearly four decades, NEB has been shaping the landscape of bioscience research by discovering, developing and supporting superior research reagents. In addition to NEB’s commitment to scientific innovation and customer relations, NEB notably ensures the environmental sustainability of the company’s business practices. Our passion is our promise.
A supplier-of-choice for scientists across the globe, NEB offers the largest selection of recombinant and native enzymes for genomic research. While restriction enzymes remain part of our core product portfolio, our ever-expanding catalog also includes products related to PCR, gene expression, cellular analysis, RNA analysis and epigenetics. Currently, NEB supplies over 276 restriction enzymes. These recombinant enzymes are available at a lower cost/unit and offer improved purity and lot-to-lot consistency. A recognized leader in the field of restriction enzymes, NEB has earned a world-wide reputation for setting the highest standards for quality and value.https://www.neb.com/
Oxford Computer Consultants is a software development company with clients across the public and private sectors. We develop custom software for energy, health and science. We provide products for social care finances. We know how to deliver the cost savings and opportunities offered by information technology.https://www.oxfordcc.co.uk/
The NIHR Biomedical Research Centre, Oxford (OxBRC) is based at the Oxford University Hospitals NHS Foundation Trust and run in partnership with the University of Oxford. It was one of five centres funded by the National Institute for Health Research (NIHR) in 2007 through a competitively awarded grant of £57m over five years. In April 2012, as a recognition for its outstanding contribution to healthcare research it was awarded a further 5 years funding at an increase of 50% to support translational research.http://oxfordbrc.nihr.ac.uk/
Thermo Fisher Scientific Inc. (NYSE: TMO) is the world leader in serving science, with revenues of $17 billion and more than 50,000 employees in 50 countries. Our mission is to enable our customers to make the world healthier, cleaner and safer. We help our customers accelerate life sciences research, solve complex analytical challenges, improve patient diagnostics and increase laboratory productivity. Through our premier brands – Thermo Scientific, Applied Biosystems, Invitrogen, Fisher Scientific and Unity Lab Services – we offer an unmatched combination of innovative technologies, purchasing convenience and comprehensive support.https://www.thermofisher.com
The Native Antigen Company (NAC) specialises in development and manufacture of native and recombinant viral and bacterial antigens. NAC’s antigens are used by pharmaceutical and IVD manufacturers in vaccine research and serology where proper folding and glycosylation are vital. As well as offering antigens from a rapidly expanding portfolio, NAC undertakes bespoke product development and custom manufacture using its proprietary mammalian cell protein expression system.https://thenativeantigencompany.com/
The better the source, the more to eXplore.
Our mission is to enable and improve the diagnosis, treatment and monitoring of disease by providing clinicians and researchers with preanalytical systems that yield superior quality samples for molecular diagnostic testing. PAXgene products integrate and standardize the collection, transport, storage, stabilization and purification of nucleic acids from human specimens to optimize the analysis of clinically relevant biomarkers.http://www.preanalytix.com/
STEMCELL Technologies Inc is a privately-owned biotechnology company that develops specialty cell culture media, cell separation products and ancillary reagents for life science research. Driven by science and a passion for quality, STEMCELL delivers over 1500 products to more than 70 countries worldwide.
STEMCELL helps make sure your research works. We do it in many ways: in the creativity of novel products; in providing consistent, unfailing quality; and by standing with you, in person or by telephone, to provide one-on-one assistance to help you succeed. We do this because we love science as much as you do.http://www.stemcell.com/
Uncovering the Potential of Natural Ingredients.
Sibelius is a scientifically led company that works with leading product researchers and developers to create, test and commercialise innovative and efficacious natural products. It works at the cutting edge, by offering unique insights into the epigenetics of age-related conditions.
Epigenetics is an increasingly powerful tool in the study of biological mechanisms that control the activity of genes without changing the under lying DNA.
If DNA is the storytelling structure of life, epigenetics is the script that writes our individual life stories, that says how long we might live, how strong we can be, how well we retain memories. We can change the script and modify the activity of our genes through natural ingredients extracted from many plants, including well-known herbs and fruits. It is the mechanism through which the environment interacts with our genome to determine our phenotype – our health status. We test a wide range of natural products, plot their effect on an increasing range of conditions associated with aging and identify their mode of action, and measure their efficacy.
Testing is usually slow and laborious, but we now have a high-throughput screen that takes weeks rather than months and years to deliver results. Working with the C.elegans model organism which has been validated in several Nobel prize-winning research projects, Sibelius has been able to dramatically reduce the costs and shorten product research and development cycles.
The Sibelius high-throughput screen opens up the exciting possibility of developing new, completely natural products that can significantly ameliorate the effects of age-related conditions. The scientific screening process allows products to be tried and developed and brought to commercial use in extremely rapid but safe timescales. Through the Sibelius system there are also methods to ensure fast patent protection of new products.
The potential of Sibelius is life-enhancing through the identification of supplements able to reset cellular network health controls. This means we can support weight management, enhance stress resistance, aid sports performance, control age-related muscle loss, better manage glucose tolerance and identify anti-oxidants to reduce inflammation, as well as enhancing the immune system and improving cognition.
So – natural, effective, safe, fast and commercial, the Sibelius approach to epigenetics brings all these benefits. It’s a science that is well recognised and validated by world-leading teams from Oxford University and MIT.
BGI, founded in 1999 with the vision of using genomics to benefit the human race, is now the world’s largest genomics organization.http://www.genomics.cn